Pyloric region. Stomach Pylorus The mucosa of the pyloric antrum possesses deep gastric pits and gastric glands. iii. D. State, Role of Pyloric Antrum in Experimentally Induced Peptic Ulceration in Dogs and others Surgery 38: (1955) 143-148 118. Antrum / pylorus: distal 3 - 4 cm Loosely packed mucous secreting glands Ratio of pit to gland volume, 50:50 Usually no cystic dilatation of glands G cells are … Enterogastrone . Inhibition of gastric secretion by acid in the antrum. VIP . 1958 May; 106 (5):545–548. b. Hormones from duodenum, e.g. Dragstedt states that, whereas the nervous phase of gastric secretion is involved in the pathogenesis of duodenal ulcer, the pyloric antrum and its hormonal mechanism seem to be implicated in benign gastric ulcer [44,45]. The antrum of the stomach contains pyloric glands and their main feature is the presence of gastrin secreting G cells. STATE D, MORGENSTERN L. The inhibitory role of the pyloric antrum on the cephalic phase of gastric acid secretion in dogs. The pylorus (/ p aɪ ˈ l ɔːr ə s / or / p ɪ ˈ l oʊ r ə s /), or pyloric part, connects the stomach to the duodenum.The pylorus is considered as having two parts, the pyloric antrum (opening to the body of the stomach) and the pyloric canal (opening to the duodenum). HCl in pyloric antrum or in duodenum (anytime when the pH of gastric contents falls below 2). DUVAL MK, Jr, PRICE WE. Stimulates secretion of gastric juice rich in HCl and pepsin . Stimuli in the brain, stomach, and small intestine activate or inhibit gastric juice production. Surg and others Forum 5: (1955) 278-280 117. There are fewer parietal cells, and most of the cells are mucosa secreting cells, which you … 1960; 10:155–160. The much larger glands of the fundus and body of the stomach, the site of most chemical digestion, produce most of the gastric secretions. Cells that make up the pyloric antrum secrete mucus and a number of hormones, including the majority of the stimulatory hormone, gastrin. D. State, L. Morganstern, Inhibitory Role of Pyloric Antrum on Cephalic Phase of Gastric Acid Secretion in Dogs Surg., Gynec. iv. ii. The secretion of gastric juice is controlled by both nerves and hormones. 106: (1958) 545-548 119. This is why the three phases of gastric secretion are called the cephalic, gastric, and intestinal phases. The glands are notable because they contain G-cells, which secrete gastrin. Actions of gastrin: Physiological actions: i. Role of the Pyloric Antrum in Regulation of Gastric Secretion Role of the Pyloric Antrum in Regulation of Gastric Secretion E. R. Woodward and L. R. Dragstedt 1960-07-01 00:00:00 HE POSSIBIL~Y that the of the stomach might elaborate a hormone which mediates the gastric or antral phase of gastric was first postulated by Edkins in 1go6 (7). Surg Forum. v. Glucagon . PHASES OF ACID SECRETION T. Antral secretion was increased after s.c. injections of histamine, carbachol and pentagastrin. JOHNSON AN, Jr, COBO A, OBERHELMAN HA, Jr, DRAGSTEDT LR. 5. Relationship Between Pyloric Antrum and Gastric Ulcer. Somatostatin secreting D cells are present in the pyloric and oxyntic glands and modulate gastrin release . Secretin . Corpus antrum boundary moves proximally with age due to reduction of oxyntic mucosal volume. The pyloric canal ends as the pyloric orifice, which marks the junction between the stomach and the duodenum. Surg Gynecol Obstet. & Obst. The mucosal (pyloric glands) in this region look different to the gastric glands in the body of the stomach.The pits are deeper, and the glands shorter and more branched. : i. GIP (gastric inhibitory polypeptide) ii.